MaherLab

Salk Institute

Research Output

Publications

21 peer-reviewed publications.

Showing 21 publications

2026

1
Glomerular hyperfiltration and enhanced sensitivity to kidney ischemia reperfusion with a blunted KIM-1 response in young male aging-accelerated SAMP8 mice

Goodluck HA, Kanoo S, Kim YC, , Maher P

American Journal of Physiology: Renal Physiology

Aging & Geroneuroprotection

2025

7
Evidence of Oxytosis/Ferroptosis in Niemann-Pick Disease Type C

Sanchez KL, Kim J, White JB, , Maher P

International Journal of Molecular Sciences, 26(7)

Oxytosis / Ferroptosis
Acid ceramidase modulates the lipid profile and exacerbates sensitivity to ferroptosis in senescent cells

Soriano-Castell D, Goujon M, Dar NJ, , Maher P

Research Square

Oxytosis / FerroptosisAging & Geroneuroprotection
Ferroptosis and Charcot-Marie-Tooth Disease 1A: Emerging Evidence for a Pathogenic Association

White JB, Sanchez KL, Currais A, , Maher P

Antioxidants, 14(3)

Oxytosis / Ferroptosis
Cannabinol (CBN) alleviates age-related cognitive decline by improving synaptic and mitochondrial health

Dar NJ, Currais A, Taguchi T, , Maher P

Redox Biology, 84, 103692

Drug DiscoveryNatural Products
Transcriptomic signatures of oxytosis/ferroptosis are enriched in Alzheimer's disease

Currais A, Sanchez K, Soriano-Castell D, , Maher P

BMC Biology, 23(1), 132

Oxytosis / FerroptosisDrug Discovery
Ferroptosis-related stress during aging and its relevance to disease

Maher P, Soriano-Castell D, Dar NJ, et al.

Geroscience

Oxytosis / FerroptosisAging & Geroneuroprotection

2024

4
The Flavonoid Fisetin Reduces Multiple Physiological Risk Factors for Dementia

Maher P

Neurochemistry International, 105805

Natural ProductsDrug Discovery
CMS121, a Novel Drug Candidate for the Treatment of Alzheimer's Disease and Age-Related Dementia

Currais A, Raschke W, Maher P

Journal of Alzheimer's Disease, 101(s1), S179-S192

Drug DiscoveryAging & Geroneuroprotection

2022

2
Cannabinol inhibits oxytosis/ferroptosis by directly targeting mitochondria independently of cannabinoid receptors

Liang Z, Soriano-Castell D, Kepchia D, , Maher P

Free Radical Biology and Medicine

Oxytosis / FerroptosisNatural ProductsDrug Discovery
The Role of AMP-activated Protein Kinase (AMPK) in Oxytosis/Ferroptosis: Protector or Potentiator?

Currais A, Kepchia D, Liang Z, , Maher P

Antioxidants and Redox Signaling

Oxytosis / Ferroptosis

2020

3
Using the Oxytosis/Ferroptosis Pathway to Understand and Treat Age-Associated Neurodegenerative Diseases

Maher P, Currais A, Schubert D

Cell Chemical Biology

Oxytosis / FerroptosisDrug Discovery
Natural products targeting mitochondria: emerging therapeutics for age-associated neurological disorders

Liang Z, Currais A, Soriano-Castell D, , Maher P

Pharmacology and Therapeutics, 107749

Natural ProductsDrug Discovery

2018

3
The mitochondrial ATP synthase is a shared drug target for aging and dementia

Goldberg J, Currais A, Prior M, , Maher P

Aging Cell, 17(2)

Drug DiscoveryAging & Geroneuroprotection
Geroneuroprotectors: Effective Geroprotectors for the Brain

Schubert D, Currais A, Goldberg J, , Maher P

Trends in Pharmacological Sciences, 39(12), 1004-1007

Aging & Geroneuroprotection