MaherLab

Salk Institute

Lab Updates

News

Announcements and updates from the Maher Laboratory.

May 1, 2025

New Study Confirms Oxytosis/Ferroptosis Signatures in Human Alzheimer's Brain

A new paper from the Maher Lab published in BMC Biology reports transcriptomic evidence of oxytosis/ferroptosis activation in human Alzheimer's disease brain samples, supporting a central role for this pathway in disease.

May 1, 2025

Cannabinol Shown to Improve Cognitive Function in Aging Mouse Model

A study from the Maher Lab published in Redox Biology demonstrates that cannabinol (CBN) significantly improves spatial learning and memory in the SAMP8 aging mouse model, with effects linked to mitochondrial and synaptic improvements.

September 1, 2024

CMS121 Advances in Clinical Trials for Alzheimer's Disease

CMS121, a drug candidate developed in the Maher Laboratory as a derivative of the flavonol fisetin, continues to advance through human clinical trials for the treatment of Alzheimer's disease.